Natural HST is an active ingredient in granular powder form consisted of sodium hyaluronate, tea tree oil, and sappan wood extract. Through the granulation, it makes possible to have a special combination, oil-soluble and water-soluble ingredients in one product, improving its solubility in water. Additionally, multiple functional activities of anti-oxidant, anti-inflammatory, anti-microbial, and sebum control effects can be exhibited at the same time.