Polygonum fagopyrum, also called buckwheat, is a nutritious dietary source of protein with favorable amino acid composition, vitamins, dietary fiber, and minerals. Buckwheat seeds and sprouts are known to contain high levels of anti-oxidants, including rutin and anthocyanin. BDS-Memil is an extract from buckwheat sprouts cultivated by Bio-Dynamic Sprout (BDS) System. BDS-Memil contains orientin, iso-orientin, rutin, and vitexin as active compounds. It shows a strong anti-oxidant activity as well as melanin inhibition activity.