Cucumis sativus is cultivated worldwide as a vegetable crop, and the fruit is used not only as food but also in folk medicines and cosmetics. Due to its high water content, it has long been used for skin care. It soothes and calms skin irritation, reduces swelling, and alleviates sunburned skin.

Cucumber contains several active compounds, including cucurbitacins, cucumegatigmanes, cucumber in A and B, vitexin, and orientin. Scientific research has shown the biological activities of cucumber, including anti-oxidant, anti-wrinkle, moisturizing, and skin brightening activities.