Guava is one of representative tropical fruits which is excellent source of vitamin C and vitamin A. Its typical fragrance is similar to lemon rind, so the oil is usually used for candle, soap and facial oil product. This fruit is also a remarkable source of natural anti-oxidants. Especially, Lycopene, one of active components of guava, is well-known for its anti-oxidant properties. Guaijaverin, a flavonoid present in guava, also known as inhibiting the growth of Streptococcus mutans, which is considered to be a pathogen for dental caries.