Natural DO is a complex of three phytoncide raw materials: pine leaf, cypress leaf, and eucalyptus leaf. These plants are well known for having anti-bacterial and anti-microbial effects. We used cold drip extraction which is applied to cold brew coffee like Dutch coffee. Using this method, we can extract active components that are weak to heat more safely and freshly. With excellent deodorization properties, it is recommended for a deodorant, detergent, or air freshener. Furthermore, it is a multifunctional product with anti-oxidant, anti-inflammatory and anti-bacterial effects.